MME Calculation:
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Morphine Milligram Equivalents (MME) is a standardized value that allows comparison between different opioid medications based on their relative potencies to morphine. It helps clinicians assess opioid dosing and risk.
The calculator uses the MME formula:
Where:
Explanation: The equation converts any opioid dose to its morphine equivalent for standardized comparison.
Details: MME calculation is crucial for opioid risk assessment, dose monitoring, and ensuring safe prescribing practices. Higher MME values are associated with increased risk of overdose and addiction.
Tips: Enter the opioid dose in mg and the appropriate conversion factor. Common conversion factors include 1 for morphine, 1.5 for oxycodone, 0.15 for buprenorphine, etc.
Q1: Why use MME calculations?
A: MME allows comparison of different opioids' potencies and helps identify patients at risk for overdose.
Q2: What are typical MME thresholds?
A: Many guidelines recommend caution above 50 MME/day and avoiding doses above 90 MME/day when possible.
Q3: Where can I find conversion factors?
A: The CDC provides standard conversion factors for most opioids. These may vary slightly by source.
Q4: Are there limitations to MME?
A: MME doesn't account for individual patient factors like metabolism, tolerance, or route of administration.
Q5: Should MME be the only factor in opioid prescribing?
A: No, clinical judgment, patient history, and risk assessment should always accompany MME calculations.